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Injuries to the nervous system result in severe loss of motor and sensory functions. Nerve autografts are widely used clinically to repair injured nerves. However, nerve grafts have many limitations, including availability and loss of function at donor site. To overcome these problems, we have used a tissue engineering approach to design three-dimensional (3D) scaffolds containing laminin-1 (LN-1) and nerve growth factor (NGF). After nerve injury and during embryonic development, several extra-cellular matrix molecules and neurotrophic factors contribute to nerve regeneration and repair. Our 3D agarose hydrogel scaffolds with gradients of LN-1 and NGF are designed to mimic these in vivo conditions to promote nerve regeneration in rats. These scaffolds have shown to promote nerve regeneration comparable to using nerve autografts in rats. This book, therefore, provides a novel technique of nerve scaffold preparation for greater success in nerve regeneration. Scientists and students of neural engineering could use this technique to design novel scaffolds. Optimization of this technique could result in a viable alternative to using nerve grafts for nerve regeneration.

Could anything possibly be more fun than a pig parade!? You wouldn't think so. But you'd be wrong. A pig parade is a terrible idea. Pigs hate to march, refuse to wear the uniforms, don't care about floats, and insist on playing country music ballads. Those are just some of the reasons. And trust me, this hysterical book has plenty more! "Fragments "is an event an unforgettable book that will redefine one of the greatest icons of the twentieth century and that, nearly fifty years after her death, will definitively reveal Marilyn Monroe's humanity.Marilyn's image is so universal that we can't help but believe we know all there is to know of her. Every word and gesture made headlines and garnered controversy. Her serious gifts as an actor were sometimes eclipsed by her notoriety and by the way the camera fell helplessly in love with her.Beyond the headlines and the too-familiar stories of heartbreak and desolation was a woman far more curious, searching, witty, and hopeful than the one the world got to know. Now, for the first time, readers can meet the private Marilyn and understand her in a way we never have before. "Fragments "is an unprecedented collection of written artifacts notes to herself, letters, even poems in Marilyn's own handwriting, never before published, along with rarely seen intimate photos.Jotted in notebooks, Tissue Engineered Scaffolds for Nerve Regeneration pdf typed on paper, or written on hotel letterhead, these texts reveal a woman who loved deeply and strove to perfect her craft. They show a Marilyn Monroe unsparing in her analysis of her own life, but also playful, funny, and impossibly charming. The easy grace and deceptive lightness that made her performances indelible emerge on the page, as does the simmering tragedy that made her last appearances so affecting."

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Author: Mahesh Chandra Dodla
Number of Pages: 164 pages
Published Date: 01 Feb 2008
Publisher: VDM Verlag Dr. Mueller e.K.
Publication Country: Saarbrucken, Germany
Language: English
ISBN: 9783836457637
Download Link: Click Here
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